Xa uceba ukuthenga izixhobo zechromatography elulwelo kuphando lwebhubhoratri okanye uvavanyo lwamashishini, unokukhathazwa luthotho lwemibuzo. Loluphi uhlobo lwechromatography elulwelo lufaneleke kakhulu kwiimfuno zakho zohlalutyo lwesampulu, ezinjengokwahlula iikhompawundi zezinto eziphilayo ezibilayo okanye ukulandelela iimolekyuli zebhayoloji? Ungaqinisekisa njani ukuba izixhobo ezikhethiweyo ziyahlangabezana nokuchaneka okungqongqo kunye neemfuno zovakalelo kushishino lwakho? Kwaye ngaba uyawuqonda ngokucacileyo umahluko kwiimeko zesicelo phakathi kweemodeli ezahlukeneyo zechromatography yolwelo, ukuze uthintele ukungahambelani phakathi kwemisebenzi yezixhobo kunye nemisebenzi yokwenyani yovavanyo?
Ichromatography yolweloItekhnoloji yohlalutyo engundoqo esetyenziswa kakhulu kwimimandla efana ne-biopharmaceuticals, ukhuseleko lokutya, kunye nokubeka iliso kokusingqongileyo. Ukuqonda iintlobo zayo ezithile kunye neempawu kubalulekile ekukhetheni izixhobo ezifanelekileyo. Oku kulandelayo kuya kunika iinkcukacha ngeentlobo, iindidi zemveliso yophawu, izibonelelo, amabakala ezinto eziphathekayo, kunye nemimandla yesicelo sechromatography yolwelo ukukunceda wenze izigqibo ezinolwazi.
Iindidi eziqhelekileyo zeChromatography yolwelo
Kwimarike, i-chromatography yolwelo yahlulwe ikakhulu kwiindidi ezininzi ngokusekwe kwimigaqo yokwahlula kunye neemeko zesicelo. I-High-Performance Liquid Chromatography (HPLC) yolona hlobo lusetyenziswa kakhulu, olunolwahlulo oluphezulu olusebenzayo kunye nesantya sohlalutyo olukhawulezayo, olufanelekileyo kuninzi lokufumanisa i-organic compound. I-Ultra-High Performance Liquid Chromatography (UHPLC) inokumelana noxinzelelo oluphezulu kunye novelwano olungcono, olunokunciphisa ixesha lokuhlalutya ngaphezu kwe-50% xa kuthelekiswa ne-HPLC kwaye isetyenziswa rhoqo kwiimeko zokuvavanya okuphezulu. I-Two-Dimensional Liquid Chromatography (2D-LC) idibanisa iinkqubo ezimbini ezahlukeneyo zokwahlula, ukwandisa uluhlu lwezinto ezibonakalayo kwaye zisebenza ekuhlolweni kweematriki ezinzima ezifana ne-serum exogenous exposure. Ukongeza, kukho iindidi ezikhethekileyo ezinje nge-Ion-Exchange Chromatography yokwahlulwa kwekhompawundi ye-ionic kunye nobukhulu-Ukukhutshwa kweChromatography yohlalutyo lwento ye-macromolecular.
Iindidi zeChromatography yeMaxi yeNzululwazi
I-Maxi Scientific Instruments (i-Suzhou) Co., Ltd., igxile kwintsimi ye-chromatography, inika uluhlu olupheleleyo lweemveliso ezinxulumene ne-chromatography yolwelo. Iimveliso zayo eziphambili zibandakanya iiKholamu ze-Ghost-Sniper kunye nokusebenza ngokuthelekiswa neemveliso zangaphambili, izixhobo ze-PEEK HPLC, kunye ne-316L yensimbi engenasici. Ezi mveliso zineengenelo zamaxabiso afikelelekayo, amaxesha amafutshane okuhanjiswa, kunye nokuxhathisa okuqinileyo kokutya. Ngokomzekelo, i-316L i-capillary yensimbi engenasici ithatha inkqubo ekhethekileyo yokukhusela, engenamsebenzi wokutywina obalaseleyo kuphela kodwa inokufakwa lula ngesandla, ilungele ukuhambelana neenkqubo ezahlukeneyo ze-chromatography zamanzi.
I-Advanteji ye-Liquid Chromatography
Ngokubhekiselele kwizinto eziluncedo ngokubanzi, i-chromatography yolwelo inokuhlalutya i-80% yeekhompawundi ze-organic, ngakumbi ukubilisa okuphezulu, ukungazinzi kwe-thermal, kunye ne-biologically esebenzayo ekunzima ukuyiphatha nge-chromatography yegesi. Ukuqonda kwayo ukufumanisa kuphezulu, kwaye i-ultraviolet detector inokufikelela kwi-0.01ng, enokuthi ihlangabezane neemfuno zokuhlalutya umkhondo.
Kwiintlobo eziqhelekileyo, i-HPLC ineenzuzo zekholamu ezisebenzisekayo kunye nokusetyenziswa kwesampuli encinci; I-UHPLC inokusebenza kakuhle kokuhlula (izihlandlo ezithathu ze-HPLC eqhelekileyo) kunye nesantya esisezantsi sokungcoliseka; I-2D-LC inokwandisa i-oil-water partition-coefficient uluhlu lwezinto ezibonakalayo ukuya kwi-8 ukuya kwi-12, iqonda ukuba i-high-coverage screening yezinto ezingcolisayo ezininzi.
Iimveliso zeMaxi Scientific zineenzuzo ezizodwa. IKholamu yayo ye-Ghost-Sniper ithatha inkqubo yokuvelisa ekhethekileyo, eqinisekisa ukusebenza okuzinzile ngelixa kunciphisa iindleko. Iimveliso ze-capillary zinobomi obude benkonzo, enokunciphisa ukuphindaphinda kokutshintshwa kwezixhobo kubasebenzisi kunye nokugcina iindleko zokusebenza.
ILiquid Chromatography Material amaBanga
Izinto ezingundoqo zechromatography zolwelo zinemigangatho engqongqo yemathiriyeli. Ukuthatha ikholomu njengomzekelo, isigaba esimileyo sisebenzisa iinqununu ezinobunzima kunye nobukhulu be-5-10μm ye-HPLC kunye neencinci ezincinci ze-UHPLC ukuphucula ukusebenza kakuhle kokuhlukana. Umbhobho wenziwa kakhulu nge-316L yensimbi engenasici (i-corrosion-resistant) okanye i-PEEK impahla (efanelekile kwi-asidi eqinile kunye neesampuli ze-alkali).
Ngokwemigangatho yebakala loshishino, izixhobo kufuneka zihlangabezane nezalathisi zokusebenza ezifana nokuchaneka kwesantya sokuhamba (± 1% okanye ± 2μL / min) kunye nokuzinza kokulawula ubushushu (± 0.1℃). Umzekelo, iimveliso zeMaxi Scientific zithobela ISO9001:2015 isiqinisekiso senkqubo yolawulo lomgangatho, iqinisekisa ukuba umgangatho wemveliso uyahlangabezana nemigangatho yamazwe ngamazwe.
Ukusetyenziswa kweChromatography yolwelo
Kwintsimi ye-biopharmaceuticals, i-chromatography yolwelo isetyenziselwa ukuhlanjululwa kweeprotheyini kunye nokulawula umgangatho weziyobisi. Ngokomzekelo, inokwahlula kwaye ibone i-amino acids kunye neepeptides kwiisampuli zebhayoloji. Ekuvavanyeni ukhuseleko lokutya, inokuhlalutya izongezo zokutya ezifana nezigcini kunye nezingcolisi ezifana neentsalela ze-pesticide, kunye nomda wokufumanisa ophantsi njengamanqanaba omkhondo. Kuhlolo lokusingqongileyo, isetyenziselwa ukubona izinto ezingcolisa indalo ezifana neepolycyclic aromatics hydrocarbons kunye neephenols emanzini nasemhlabeni.
Iimveliso zeMaxi Scientific ziye zasetyenziswa kwiinkalo ezininzi. Kwiprojekthi yohlalutyo lokutya, iKholamu yayo ye-Ghost-Sniper igqibe ngempumelelo ukwahlula kunye nokufumanisa izongezo zokutya ezininzi, kunye nezinga lokubuyisela ngaphezu kwe-95% kunye nedatha ezinzileyo. Kwiprojekthi yokuvavanya indalo, i-316L yensimbi engenasici ye-capillary ehambelana nenkqubo ye-chromatography ye-liquid yaqonda ukubeka iliso okuqhubekayo kweesampuli zamanzi kwiiyure ze-240, ukuqinisekisa ukuchaneka kweziphumo zovavanyo.
Ukuqukumbela
I-chromatography ye-Liquid ineentlobo ezininzi ezifana ne-HPLC, i-UHPLC, kunye ne-2D-LC, nganye ineenzuzo ezizodwa kunye neemeko ezisebenzayo. Iimveliso ezinxulumene nekhromatografi yeMaxi Scientific, ezinomgangatho ophezulu wokusebenza, ukufikeleleka, kunye nomgangatho othembekileyo, zinokuhlangabezana neemfuno zamashishini ahlukeneyo. Nokuba ubandakanyeka kuphando lwe-biopharmaceutical, uvavanyo lokhuseleko lokutya, okanye ukubeka iliso kokusingqongileyo, ukukhetha iimveliso ze-Maxi Scientific kunokukunceda uphucule uhlalutyo olusebenzayo kunye nokunciphisa iindleko. Ngoku, nceda uqhagamshelane ne-Maxi Scientific ngoko nangoko (fowunela +86 400-6767580) ukufumana iikowuti zemveliso kunye neenkonzo zokubonisana zokuthengisa kwangaphambili!
Ixesha lokuposa: Nov-26-2025